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In animal systems, LLPS-driven higher-order assemblies operate not only at the level of upstream signal sensing but also penetrate into the execution layeras seen in the NLRP3ASC speck during pyroptosis or the assembly of the DISC in apoptosis

150 PengD.LiL.WeiA.ZhouL.WangB.LiuM.et al

Imaging parameters included: 1,024 1,024-pixel scan, 16-bit depth, speed of 600, pixel averaging of 2, pinhole of 1 AU and acquisition using a 63 oil-immersion lens (NA 1.4, 14 zoom)